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  1. NTU Scholars
  2. 醫學院
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Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/588273
Title: Treatment of electronic cigarette or vaping product use-associated lung injury (EVALI) by corticosteroid and low-dose pirfenidone: Report of a case
Authors: Wu, Chia-Hao
Liao, Ting-Yu
YUNG-HSUAN CHEN 
PING-HUNG KUO 
Keywords: corticosteroid; e‐cigarette or vaping product use associated lung injury (EVALI); organizing pneumonia; pirfenidone;corticosteroid; e-cigarette or vaping product use associated lung injury (EVALI); organizing pneumonia; pirfenidone
Issue Date: Oct-2021
Journal Volume: 9
Journal Issue: 10
Source: Respirology case reports
Abstract: 
Electronic (e)-cigarette or vaping product use-associated lung injury (EVALI) is a novel and potentially lethal disease first reported in the United States. We report the case of a 56-year-old man who presented to our hospital with dyspnoea and cough lasting for 2 months after using an e-cigarette for approximately 50 puffs over 2 weeks. Physical examination revealed crackles in the left lower lung. High-resolution computed tomography (HRCT) showed consolidation and ground-glass opacities in both lungs. The baseline forced vital capacity (FVC) and diffusion capacity for carbon monoxide (DLCO) were 65.7% and 63.9% of the predicted, respectively. Lung biopsy revealed organizing pneumonia with focal fibrosis. In addition to prednisolone, he was treated with a low-dose pirfenidone (200 mg three times per day) due to the persistence of a mild cough, exertional dyspnoea and basal crackles after discharge. His symptoms and FVC significantly improved, but the recovery of the DLCO was slow. The follow-up HRCT demonstrated only minimal fibrotic changes. To our knowledge, this was the first reported case of EVALI successfully treated with a combination of corticosteroid and antifibrotic agents.
URI: https://scholars.lib.ntu.edu.tw/handle/123456789/588273
ISSN: 2051-3380
DOI: 10.1002/rcr2.845
SDG/Keyword: antifibrotic agent; azathioprine; corticosteroid; cyclophosphamide; methylprednisolone; mycophenolic acid; pirfenidone; prednisolone; adult; Article; blood pressure; breathing rate; case report; clinical article; computer assisted tomography; corticosteroid therapy; coughing; crackle; diffusing capacity for carbon monoxide; dyspnea; exertional dyspnea; forced expiratory volume; forced vital capacity; high resolution computer tomography; human; leukocyte count; low drug dose; lung biopsy; lung function test; male; middle aged; oxygen saturation; physical examination; vaping associated lung injury
[SDGs]SDG3
Appears in Collections:醫學系

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臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
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開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

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