https://scholars.lib.ntu.edu.tw/handle/123456789/588765
Title: | State of the antiretroviral therapy in human immunodeficiency virus drug resistance: Surveillance and regional gaps | Authors: | Boucher C.A. Bobkova M.R. CHIEN-CHING HUNG Kaiser R. Marcelin A.-G. Streinu-Cercel A. van Wyk J. Dorr P. Vandamme A.-M. |
Keywords: | Epidemiology; Guidelines; Human immunodeficiency virus drug resistance; Regional practice; Resistance surveillance | Issue Date: | 2018 | Publisher: | Publicaciones Permanyer | Journal Volume: | 20 | Journal Issue: | 1 | Start page/Pages: | 42-56 | Source: | AIDS Reviews | Abstract: | This article is (he second of a two-part review aiming to identify gaps in the knowledge and management of human immunodeficiency virus type 1 drug resistance (HIVDR) from global and regional perspectives. Here, we examine the policy and programmatic gaps in HIVDft surveillance, the affected populations and settings, and implications for clinical practice. The expert authorship of this review convened to identify gaps in HIVDR surveillance, with a particular focus on specific regional variations within and between Europe and Asia, to highlight directions tor research and implementation. Further, evidence was gathered from a review of published studies, guidelines, and current practices. This review found that despite recent progress in the development, harmonization, and implementation of guidelines on H/VDft reporting and surveillance, programmatic, and policy gaps reflect the regional variability in HIV epidemics, clinical practice, and resources. The need for representative surveillance was identified as a key gap that has the potential to inform management policies. Monitoring must keep up with the evolution of transmission routes to adapt appropriately, and this will be further impacted by migration from areas with increasing levelsol resistance. Analysis of the latest clinical data, regional practice, policy, and guidelines has identified a number of gaps in HIVDR population monitoring and surveillance. More efforts are needed to align surveillance platforms with harm reduction and patient education, particularly in vulnerable subgroups. Addressing these gaps will facilitate research into and progress in the management of HIV across a wide range of health-care settings. ? 2018, Publicaciones Permanyer. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85045515631&doi=10.24875%2fAIDSRev.M17000019&partnerID=40&md5=45c516c5edde4e7002861b8ba6acd141 https://scholars.lib.ntu.edu.tw/handle/123456789/588765 |
ISSN: | 1139-6121 | DOI: | 10.24875/AIDSRev.M17000019 | SDG/Keyword: | antiretrovirus agent; integrase inhibitor; antiretroviral therapy; antiviral resistance; Article; Asia; clinical practice; consensus development; disease surveillance; epidemic; epidemiological monitoring; Europe; funding; harm reduction; health care policy; HIV education; human; Human immunodeficiency virus 1 infection; men who have sex with men; minority group; patient education; prevalence; standardization; virus mutation; virus transmission |
Appears in Collections: | 醫學系 |
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