ATMIN Suppresses Metastasis by Altering the WNT-Signaling Pathway via PARP1 in MSI-High Colorectal Cancer
Journal
Annals of surgical oncology
Journal Volume
28
Journal Issue
13
Date Issued
2021-12
Author(s)
Abstract
Constant DNA damage occurs in cells, and the cells are programmed to respond constitutively. This study explored the roles of ataxia-telangiectasia mutated interactor (ATMIN), one of the impaired pathways involving the DNA damage response (DDR) in mismatch repair-deficient [microsatellite instability (MSI)-high] colorectal carcinoma (CRC).
SDGs
Other Subjects
ataxia telangiectasia mutated interactor; beta catenin; messenger RNA; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase 1; olaparib; protein; transcription factor 4; unclassified drug; ATMIN protein, human; nicotinamide adenine d
Type
journal article