https://scholars.lib.ntu.edu.tw/handle/123456789/590595
標題: | Multifocal leukoencephalopathy induced by levamisole: A case report | 作者: | Wang C.-H. JIANN-SHING JENG Yip P.-K. |
關鍵字: | Demyelinating disease; Levamisole; Multifocal leukoencephalopathy | 公開日期: | 2002 | 卷: | 11 | 期: | 4 | 起(迄)頁: | 205-208 | 來源出版物: | Acta Neurologica Taiwanica | 摘要: | A 24-year-old woman developed progressive dysarthria and right hemiparesis following 6 months' course of levamisole treatment for recurrent oral ulcer (a total dose of 5400 mg). Her head magnetic resonance images showed multifocal white matter lesions with rim enhancement. The results of cerebrospinal fluid analysis and evoked potential studies were normal. After receiving steroid pulse therapy and then gradual tapering of the steroids, she had marked clinical and radiographic improvement. Multifocal leukoencephalopathy has been associated with the administration of 5-fluorouracil (5-FU) and levamisole respectively or in combination. Identification of this syndrome is important, because early cessation of the causative agents and possibly a short course of steroid treatment would lead to early resolution. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036892155&partnerID=40&md5=c67e39c8e627bae0361f4466d47542e2 https://scholars.lib.ntu.edu.tw/handle/123456789/590595 |
ISSN: | 10196099 | SDG/關鍵字: | fluorouracil; levamisole; adult; article; case report; cerebrospinal fluid analysis; clinical feature; disease course; dysarthria; evoked response; female; hemiparesis; human; nuclear magnetic resonance imaging; progressive multifocal leukoencephalopathy; steroid therapy |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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