Molecular diagnosis and therapy for cutaneous leishmaniasis of a returned traveler from Mexico
Journal
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
Journal Volume
54
Journal Issue
6
Pages
1154
Date Issued
2021-12
Author(s)
Tsai, Pei-Hsuan
Chen, Yu-Ting
Huang, Miao-Hui
Yeong, Eng-Kean
Abstract
Leishmaniasis is prevalent in Southern Europe, the Middle East, India, Africa, and Central and South America. Cutaneous leishmaniasis may spontaneously heal over time without treatment; however, risk of visceral dissemination and the impact of cosmetic defect are important concerns. We report a Case of cutaneous leishmaniasis in a patient who ever traveled to Mexico before the onset of a deteriorating wound around the swollen left eyebrow. A diagnosis of infection with Leishmania mexicana was made based on histopathological examination and molecular identification. Systemic treatment with liposomal amphotericin B and ketoconazole were administered with gradual healing of the lesion. Also, this traveler case implicates that the spread of endemic parasitic diseases may be a concealed risk on the public health for Taiwan underlying globalization.
Subjects
Cutaneous leishmaniasis; Ketoconazole; Leishmania mexicana; Liposomal amphotericin B; Taiwan
SDGs
Other Subjects
amphotericin B; amphotericin B lipid complex; ketoconazole; protozoal DNA; adult; case report; cutaneous leishmaniasis; genetics; human; isolation and purification; Leishmania mexicana; male; pathology; travel related disease; treatment outcome; Adult; Amphotericin B; DNA, Protozoan; Humans; Ketoconazole; Leishmania mexicana; Leishmaniasis, Cutaneous; Male; Travel-Related Illness; Treatment Outcome
Publisher
ELSEVIER TAIWAN