DEK-AFF2 fusion-associated papillary squamous cell carcinoma of the sinonasal tract: clinicopathologic characterization of seven cases with deceptively bland morphology
Journal
Modern Pathology
Journal Volume
34
Journal Issue
10
Pages
1820-1830
Date Issued
2021
Author(s)
Kuo Y.-J.
Lewis J.S.
Jr.
Zhai C.
Chen Y.-A.
Chernock R.D.
Lan M.-Y.
Lee C.-K.
Weinreb I.
Hang J.-F.
Abstract
A novel DEK-AFF2 fusion has been recently identified in four cases of basaloid to nonkeratinizing squamous cell carcinoma (SCC) in the sinonasal tract and middle ear with high-grade morphology. The exceptional response to immune checkpoint inhibitor in th
SDGs
Other Subjects
epidermal growth factor receptor; immune checkpoint inhibitor; K ras protein; protein p40; protein p63; adult; aged; Article; cancer morphology; carcinoma in situ; chemoradiotherapy; clinical article; clinical feature; DEK AFF2 gene fusion; disease course
Publisher
Springer Nature
Type
journal article