Repository logo
  • English
  • 中文
Log In
Have you forgotten your password?
  1. Home
  2. College of Medicine / 醫學院
  3. School of Medicine / 醫學系
  4. Risk of fractures in vitiligo patients treated with phototherapy-A retrospective population-based cohort study
 
  • Details

Risk of fractures in vitiligo patients treated with phototherapy-A retrospective population-based cohort study

Journal
Journal of Dermatological Science
Journal Volume
82
Journal Issue
3
Pages
197-203
Date Issued
2016
Author(s)
Lo P.-C.
Li C.-Y.
Huang W.-F.
Tsai Y.-W.
Liu H.-N.
Chang Y.-T.
HSIEN-YI CHIU  
TSEN-FANG TSAI  
DOI
10.1016/j.jdermsci.2016.02.010
URI
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960539691&doi=10.1016%2fj.jdermsci.2016.02.010&partnerID=40&md5=7cf256ef0edbfb39f4e750f572bfac2e
https://scholars.lib.ntu.edu.tw/handle/123456789/592070
Abstract
Background: Phototherapy might increase bone mineral density. However, it is unknown whether phototherapy can reduce the risk of fractures in patients with vitiligo. Objectives: To investigate the effect of phototherapy on fracture risks in vitiligo patients aged 40 or older. Methods: This population-based cohort study used the 2000-2010 Taiwan National Health Insurance Research Database (NHIRD) to identify 3863 patients newly diagnosed with vitiligo between 2003 and 2009 at age ?40 years. Study subjects were classified into three cohorts: (1) frequent phototherapy; (2) infrequent phototherapy; and (3) no phototherapy. Patients were followed until the first hip or vertebral fracture or 31 December 2010. Data were analysed using Cox regression models and also stratified by age and gender. Results: Frequent phototherapy decreased the fracture risks (adjusted hazard ratio (aHR) = 0.32, p = 0.009) in vitiligo patients. Stratification by age and gender confirmed the fracture prevention effect of frequent phototherapy in patients aged 40-64 years (aHR = 0.14, p = 0.016) and in female patients (aHR = 0.31, p = 0.024). Conclusions: This study provides the first evidence that frequent phototherapy can reduce the risk of fractures among middle-aged and among female vitiligo patients. ? 2016.
SDGs

[SDGs]SDG3

Other Subjects
adult; age distribution; Article; cohort analysis; controlled study; female; fracture; human; major clinical study; male; middle aged; national health insurance; outcome assessment; phototherapy; population research; priority journal; retrospective study; risk assessment; risk reduction; sex difference; Taiwan; therapy effect; vitiligo; age; aged; bone density; Hip Fractures; proportional hazards model; radiation response; risk; Spinal Fractures; vitiligo; Adult; Age Factors; Aged; Bone Density; Female; Hip Fractures; Humans; Male; Middle Aged; Phototherapy; Proportional Hazards Models; Retrospective Studies; Risk; Sex Factors; Spinal Fractures; Taiwan; Vitiligo
Publisher
Elsevier Ireland Ltd
Type
journal article

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

  • 請確認所上傳的全文是原創的內容,若該文件包含部分內容的版權非匯入者所有,或由第三方贊助與合作完成,請確認該版權所有者及第三方同意提供此授權。
    Please represent that the submission is your original work, and that you have the right to grant the rights to upload.
  • 若欲上傳已出版的全文電子檔,可使用Open policy finder網站查詢,以確認出版單位之版權政策。
    Please use Open policy finder to find a summary of permissions that are normally given as part of each publisher's copyright transfer agreement.
  • 網站簡介 (Quickstart Guide)
  • 使用手冊 (Instruction Manual)
  • 線上預約服務 (Booking Service)
  • 方案一:臺灣大學計算機中心帳號登入
    (With C&INC Email Account)
  • 方案二:ORCID帳號登入 (With ORCID)
  • 方案一:定期更新ORCID者,以ID匯入 (Search for identifier (ORCID))
  • 方案二:自行建檔 (Default mode Submission)
  • 方案三:學科館員協助匯入 (Email worklist to subject librarians)

Built with DSpace-CRIS software - Extension maintained and optimized by 4Science