|Title:||Assessment of preferred methods to measure insulin resistance in Asian patients with hypertension||Authors:||Minh, Huynh Van
Tien, Hoang Anh
Sinh, Cao Thuc
Thang, Doan Chi
Tay, Jam Chin
Sogunuru, Guru Prasad
|Keywords:||Asia patients; hypertension; insulin resistance;Asia patients; hypertension; insulin resistance||Issue Date:||Mar-2021||Publisher:||WILEY||Journal Volume:||23||Journal Issue:||3||Start page/Pages:||529||Source:||Journal of clinical hypertension (Greenwich, Conn.)||Abstract:||
Insulin resistance (IR), a metabolic risk factor, is linked to the pathogenetic mechanism of primary hypertension. Detecting IR in the patients with hypertension will help to predict and stratify the added cardiovascular risk, institute appropriate IR management, and manage hypertension optimally. There are many methods for assessing IR, each with distinct advantages and disadvantages. The euglycemic insulin clamp and intravenous glucose tolerance test, gold standards for measuring IR, are used in research but not in clinical practice. Homeostatic model assessment (HOMA-IR), a method for assessing β-cell function and IR, is frequently applied presently, particularly in Asia. Besides, the triglyceride-glucose index (TyG) first published by South American authors showed a good correlation with the insulin clamp technique and HOMA-IR index. This simple, convenient, and low-cost TyG index is of research interest in many countries in Asia and can be used to screen for IR in the Asian hypertensive community.
|URI:||https://scholars.lib.ntu.edu.tw/handle/123456789/592765||ISSN:||1524-6175||DOI:||10.1111/jch.14155||metadata.dc.subject.other:||glucose; insulin; insulin; triacylglycerol; Asia; Asian; disease association; endocrine pancreas function test; essential hypertension; euglycemic insulin clamp; glucose blood level; glucose clamp technique; glucose insulin ratio; heritability; homeostasis model assessment; human; hyperinsulinemia; hyperinsulinemic-euglycemic clamp technique; hypertension; incidence; insulin blood level; insulin resistance; insulin suppression test; insulin tolerance test; intravenous glucose tolerance test; mass screening; Matsuda index; metabolic parameters; oral glucose tolerance test; pancreas islet beta cell; pancreas islet cell function; pathogenesis; pathophysiology; prevalence; Quantitative Insulin Sensitivity Check Index; rapid insulin sensitivity test; Review; triglyceride glucose index; triglyceride glucose index body mass index; triglyceride glucose index waist circumference; triglyceride waist to height ratio; hypertension; insulin resistance; Asia; Blood Glucose; Humans; Hypertension; Insulin; Insulin Resistance; Triglycerides
|Appears in Collections:||醫學系|
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