https://scholars.lib.ntu.edu.tw/handle/123456789/593850
標題: | Effect of Perineural Injection with Different Dextrose Volumes on Median Nerve Size, Elasticity and Mobility in Hands with Carpal Tunnel Syndrome | 作者: | MENG-TING LIN Liu, I-Chun Syu, Wei-Ting PO-LING KUO CHUEH-HUNG WU |
關鍵字: | elasticity imaging techniques; median nerve; nerve compression syndromes | 公開日期: | 9-五月-2021 | 出版社: | MDPI | 卷: | 11 | 期: | 5 | 來源出版物: | Diagnostics | 摘要: | This study aimed to investigate the effect of different injectate volumes on ultrasonographic parameters and the correlation to clinical outcomes under perineural dextrose injection (PDI). In this post hoc analysis of the randomized, double-blinded, three-arm trial, ultrasound-guided PDI with either 1 mL, 2 mL, and 4 mL 5% dextrose water was administered, respectively, in 14, 14, and 17 patients. Ultrasound outcomes included mobility, shear-wave elastography (SWE), and cross-sectional area (CSA) of the median nerve; clinical outcomes were Visual Analog Scale (VAS) and Boston Carpal Tunnel Questionnaire (BCTQ) score. Outcomes were measured before injection, and after injection at the 1st, 4th, 12th, and 24th week. For ultrasound outcomes, CSA decreased significantly from baseline data at all follow-up time-points in the 2 mL group (p = 0.005) and the 4 mL group (p = 0.015). The mean change of mobility from baseline showed a greater improvement on the 4 mL group than the other groups at the 1st week post-injection. For clinical outcomes, negative correlation between the VAS and mobility at the 1st (p = 0.046) and 4th week (p = 0.031) post-injection in the 4 mL group were observed. In conclusion, PDI with higher volume yielded better nerve mobility and decreased CSA of median nerve, but no changes of nerve elasticity. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/593850 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85106514170&doi=10.3390%2fdiagnostics11050849&partnerID=40&md5=5da6cce408f83ebbc7bd0d2cca884ff7 |
ISSN: | 20754418 | DOI: | 10.3390/diagnostics11050849 |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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