Insomnia and the risk of atrial fibrillation: A population-based cohort study
Journal
Acta Cardiologica Sinica
Journal Volume
33
Journal Issue
2
Pages
165-172
Date Issued
2017
Author(s)
Abstract
Background: Although advancements in the treatment of atrial fibrillation have improved patient prognosis for this persistent condition, interest in atrial fibrillation development is growing. Of note is the fact that additional attention is being focused on the accompanying effect of insomnia. The aim of the study was to investigate the effects of insomnia on the risk of atrial fibrillation development. Methods: This was a nationwide population-based retrospective cohort study using data fromthe Taiwan National health Insurance Research Database. We analyzed 64,421 insomnia cases and 128,842 matched controls without insomnia from January 1, 2000, to December 31, 2010. A Cox regression model was used to estimate the adjusted hazard ratios (HRs) and 95% confidence intervals (CI) for atrial fibrillation development. Results: During the follow-up period, the incidence of atrial fibrillation development was significantly higher in the insomnia cases than in the comparison cohort (2.6% vs. 2.3%, p < 0.001). Insomnia was associated with an increased risk of atrial fibrillation (HR = 1.08, 95% CI: 1.01-1.14).Males, those > 65 years of age, and patients with peripheral artery disease who have insomnia had a higher rate of atrial fibrillation development. Conclusions: The findings of this nationwide analysis support the hypothesis that insomnia is associated with a significant risk of atrial fibrillation development. ? 2017, Republic of China Society of Cardiology. All rights reserved.
Subjects
Atrial fibrillation
Cohort study
Insomnia
SDGs
Other Subjects
adult; Article; atrial fibrillation; bipolar disorder; chronic kidney failure; clinical outcome; comorbidity; congestive heart failure; controlled study; coronary artery disease; depression; diabetes mellitus; disease free survival; dyslipidemia; female; hospitalization; human; hypertension; ICD-9-CM; insomnia; major clinical study; male; peripheral occlusive artery disease; retrospective study; risk; sleep disordered breathing; valvular heart disease
Publisher
Republic of China Society of Cardiology
Type
journal article