|Title:||Age, male gender, and atrial fibrillation predict lower extremity amputation or revascularization in patients with peripheral artery diseases: A population-based investigation||Authors:||JIEN-JIUN CHEN
|Issue Date:||2012||Journal Volume:||21||Journal Issue:||1||Start page/Pages:||35-39||Source:||International Journal of Angiology||Abstract:||
By using the National Health Insurance (NHI) claim data of Taiwan, we sought to determine the predictors for nontraumatic lower extremity amputation (LEA) or peripheral revascularization procedures (PRP) in patients with peripheral artery disease (PAD). From the NHI claim data, we identified 12,206 patients with newly diagnosed PAD between 1998 and 2008, and followed them up to 2008. We explored the age, gender, and whether the patients had concomitant comorbid conditions, such as diabetes mellitus (DM), hypertension (HTN), atrial fibrillation (AF), stroke, hospitalization for coronary artery disease (CAD), myocardial infarction (MI), or heart failure (HF), and whether they were taking cilostazol at the time of recruitment. We searched for clinical parameters that might be important determinants for LEA or PRP in the study population. Of the 12,206 patients, 150 (1.2%) were found to undergo either LEA or PRP or both (LEA 81, PRP 53, both PRP and LEA 16). Old age, male gender, and history of hospitalization for CAD or MI and AF were found to be risk predictors for both procedures. Patients with DM were at lower risk for PRP (odds ratio 0.418, p = 0.001). Patients who were taking cilostazol had higher risk for LEA or PRP. HTN was not a risk predictor for LEA or PRP. From this nationwide study, we found that among PAD patients in Taiwan, age, male gender, AF, and hospitalization for CAD or MI are risk predictors for future LEA or PRP. DM is a negative predictor for PRP while both DM and HTN are not risk predictors for LEA. Copyright ? 2012 by Thieme Medical Publishers, Inc.
|ISSN:||1061-1711||DOI:||10.1055/s-0032-1302437||SDG/Keyword:||cilostazol; adult; age; article; comorbidity; controlled study; coronary artery disease; diabetes mellitus; drug use; female; gender; heart atrium fibrillation; heart failure; heart infarction; high risk patient; hospitalization; human; hypertension; leg amputation; leg revascularization; major clinical study; male; peripheral occlusive artery disease; population research; prediction; priority journal; risk factor; sex difference; stroke; Taiwan
|Appears in Collections:||醫學系|
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