https://scholars.lib.ntu.edu.tw/handle/123456789/594699
標題: | The Rise of Colorectal Cancer in Asia: Epidemiology, Screening, and Management | 作者: | Onyoh E.F. WEN-FENG HSU LI-CHUN CHANG YI-CHIA LEE MING-SHIANG WU HAN-MO CHIU |
公開日期: | 2019 | 出版社: | Current Medicine Group LLC 1 | 卷: | 21 | 期: | 8 | 來源出版物: | Current Gastroenterology Reports | 摘要: | Purpose of Review: Colorectal cancer (CRC) remains the third most commonly diagnosed cancer globally, and its incidence and mortality rates have been on the rise in Asia. In this paper, we summarize the recent trends and screening challenges of CRC in this region. Recent Findings: In 2018, Asia had the highest proportions of both incident (51.8%) and mortality (52.4%) CRC cases (all genders and ages) per 100,000 population in the world. In addition, there has been a rising trend of this disease across Asia with some regional geographic variations. This rise in CRC can be attributed to westernized dietary lifestyle, increasing population aging, smoking, physical inactivity, and other risk factors. In curbing the rising trend, Japan, South Korea, Singapore, and Taiwan have launched nationwide population-based screening programs. CRC screening across this region has been found to be effective and cost-effective compared with no screening at all. The emergence of new therapies has caused a reduction in case fatality; however, these new options have had a limited impact on cure rates and long-term survival due to the great disparity in treatment capacity/resources and screening infrastructures among Asian countries with different degrees of economic development. Summary: CRC is still rising in Asia, and implementation of screening is necessary for moderate- to high-incidence countries and construction of treatment capacity is the priority task in low-incidence and low-income countries. Unless countries in Asia implement CRC screening, the incidence and mortality rates of this disease will continue to rise especially with the rapidly rising population growth, economic development, westernized lifestyle, and increasing aging. ? 2019, Springer Science+Business Media, LLC, part of Springer Nature. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85068757351&doi=10.1007%2fs11894-019-0703-8&partnerID=40&md5=f7dc055be03b53492e14ae9a827b9551 https://scholars.lib.ntu.edu.tw/handle/123456789/594699 |
ISSN: | 1522-8037 | DOI: | 10.1007/s11894-019-0703-8 | SDG/關鍵字: | aging; Asia; cancer incidence; cancer mortality; cancer prognosis; cancer risk; cancer screening; cancer surgery; case fatality rate; colonoscopy; colorectal cancer; diet; disease burden; economic development; human; lifestyle; long term survival; low income country; patient care; physical inactivity; population growth; prevalence; Review; smoking; survival rate; colorectal tumor; early cancer diagnosis; health survey; incidence; mass screening; procedures; prognosis; Asia; Colonoscopy; Colorectal Neoplasms; Early Detection of Cancer; Humans; Incidence; Mass Screening; Population Surveillance; Prognosis |
顯示於: | 醫學系 |
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