Real-world practice and Expectation of Asia-Pacific physicians and patients in Helicobacter Pylori eradication (REAP-HP Survey)
Journal
Helicobacter
Journal Volume
22
Journal Issue
3
Date Issued
2017
Author(s)
Abstract
Objective: The aims of the study were: 1, to survey the most popular anti-H.?pylori regimens in Asia-Pacific region and the real-world effectiveness of these regimens; and 2, to investigate the expectation gaps of eradication rate between physicians and patients. Design: A questionnaire was distributed to Asia-Pacific physicians who attended the Asia-Pacific Digestive Week 2015 meeting. Reported eradication rates from the literatures were compared with real-world rates of surveyed popular regimens within the region. In addition, a questionnaire was distributed to H.?pylori-infected patients in three regions of Taiwan. Results: A total of 691 physicians and 539 patients participated in the survey. The top five most commonly used regimens were 7-day clarithromycin-based standard triple therapy (50.4%), 14-day clarithromycin-based standard triple therapy (31.0%), 10-day sequential therapy (6.1%), 14-day bismuth quadruple therapy (3.9%), and 14-day hybrid therapy (3.6%). All countries except for China had a significant gap between the expectation of physicians on anti-H.?pylori therapy and the real-world eradication rate of most commonly adopted regimens (all P value <.05). The expectation on minimal eradication rate among patients was higher than that of physicians (91.4% vs 86.5%, P<.001). Conclusions: It is time for physicians in Asia-Pacific countries to adopt newer and more efficacious anti-H.?pylori regimens to meet the Kyoto consensus recommendation and their patients’ expectations. ? 2017 John Wiley & Sons Ltd
Subjects
expectation; Helicobacter pylori eradication; real-world practice
SDGs
Other Subjects
bismuth; clarithromycin; antiinfective agent; Article; China; clinical effectiveness; clinical practice; cost benefit analysis; doctor patient relation; drug effect; eradication therapy; expectation; health insurance; Helicobacter infection; human; major clinical study; Taiwan; treatment duration; treatment planning; Asia; clinical practice; cross-sectional study; drug therapy; female; Helicobacter infection; male; Pacific islands; procedures; questionnaire; treatment outcome; Anti-Bacterial Agents; Asia; Cross-Sectional Studies; Drug Therapy; Female; Helicobacter Infections; Humans; Male; Pacific Islands; Practice Patterns, Physicians'; Surveys and Questionnaires; Treatment Outcome
Publisher
Blackwell Publishing Ltd
Type
journal article