Chronic Granulomatous Disease: a Comprehensive Review
Journal
Clinical Reviews in Allergy and Immunology
Journal Volume
61
Journal Issue
2
Pages
101-113
Date Issued
2021
Author(s)
Abstract
Chronic granulomatous disease (CGD) is a primary immunodeficiency of phagocyte function due to defective NADPH oxidase (phox). Compared with the common types of CYBB/gp91phox, NCF1/p47phox, and CYBA/p22phox deficiency, NCF4/p40phox deficiency is a mild an
Subjects
Chronic granulomatous disease; Gene therapy; Interferon-γ; Prophylaxis; Transplantation
SDGs
Other Subjects
reduced nicotinamide adenine dinucleotide phosphate oxidase; animal; chronic granulomatous disease; gene therapy; genetics; human; neutrophil; pathology; Animals; Genetic Therapy; Granulomatous Disease, Chronic; Humans; NADPH Oxidases; Neutrophils
Publisher
Springer
Type
review