Mechanical properties of compact bone defined by the stress-strain curve measured using uniaxial tensile test: A concise review and practical guide
Journal
Materials
Journal Volume
14
Journal Issue
15
Date Issued
2021
Author(s)
Abstract
Mechanical properties are crucial parameters for scaffold design for bone tissue engineer-ing; therefore, it is important to understand the definitions of the mechanical properties of bones and relevant analysis methods, such that tissue engineers can use this information to properly design the mechanical properties of scaffolds for bone tissue engineering. The main purpose of this article is to provide a review and practical guide to understand and analyze the mechanical properties of compact bone that can be defined and extracted from the stress–strain curve measured using uniaxial tensile test until failure. The typical stress–strain curve of compact bone measured using uniaxial tensile test until failure is a bilinear, monotonically increasing curve. The associated mechanical properties can be obtained by analyzing this bilinear stress–strain curve. In this article, a computer programming code for analyzing the bilinear stress–strain curve of compact bone for quantifying the associated mechanical properties is provided, such that the readers can use this computer code to perform the analysis directly. In addition to being applied to compact bone, the information provided by this article can also be applied to quantify the mechanical properties of any material having a bilinear stress–strain curve, such as a whole bone, some metals and biomateri-als. The information provided by this article can be applied by tissue engineers, such that they can have a reference to properly design the mechanical properties of scaffolds for bone tissue engineer-ing. The information can also be applied by researchers in biomechanics and orthopedics to com-pare the mechanical properties of bones in different physiological or pathological conditions. ? 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Subjects
Biomechanics
Bone tissue engineering
Construct
Hydrogel
Orthopaedics
Orthopedics
Bone
Computer programming
Engineers
Scaffolds (biology)
Stress-strain curves
Tensile testing
Tissue
Analysis method
Computer codes
Crucial parameters
Pathological conditions
Practical guide
Strain curves
Uniaxial tensile test
Strain
Type
review