https://scholars.lib.ntu.edu.tw/handle/123456789/600221
Title: | Mechanical properties of compact bone defined by the stress-strain curve measured using uniaxial tensile test: A concise review and practical guide | Authors: | Lin C.-Y Kang J.-H. CHE-YU LIN |
Keywords: | Biomechanics;Bone tissue engineering;Construct;Hydrogel;Orthopaedics;Orthopedics;Bone;Computer programming;Engineers;Scaffolds (biology);Stress-strain curves;Tensile testing;Tissue;Analysis method;Computer codes;Crucial parameters;Pathological conditions;Practical guide;Strain curves;Uniaxial tensile test;Strain | Issue Date: | 2021 | Journal Volume: | 14 | Journal Issue: | 15 | Source: | Materials | Abstract: | Mechanical properties are crucial parameters for scaffold design for bone tissue engineer-ing; therefore, it is important to understand the definitions of the mechanical properties of bones and relevant analysis methods, such that tissue engineers can use this information to properly design the mechanical properties of scaffolds for bone tissue engineering. The main purpose of this article is to provide a review and practical guide to understand and analyze the mechanical properties of compact bone that can be defined and extracted from the stress–strain curve measured using uniaxial tensile test until failure. The typical stress–strain curve of compact bone measured using uniaxial tensile test until failure is a bilinear, monotonically increasing curve. The associated mechanical properties can be obtained by analyzing this bilinear stress–strain curve. In this article, a computer programming code for analyzing the bilinear stress–strain curve of compact bone for quantifying the associated mechanical properties is provided, such that the readers can use this computer code to perform the analysis directly. In addition to being applied to compact bone, the information provided by this article can also be applied to quantify the mechanical properties of any material having a bilinear stress–strain curve, such as a whole bone, some metals and biomateri-als. The information provided by this article can be applied by tissue engineers, such that they can have a reference to properly design the mechanical properties of scaffolds for bone tissue engineer-ing. The information can also be applied by researchers in biomechanics and orthopedics to com-pare the mechanical properties of bones in different physiological or pathological conditions. ? 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111755319&doi=10.3390%2fma14154224&partnerID=40&md5=ba02aace5d423860d11144940b9622a7 https://scholars.lib.ntu.edu.tw/handle/123456789/600221 |
ISSN: | 19961944 | DOI: | 10.3390/ma14154224 |
Appears in Collections: | 應用力學研究所 |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.