https://scholars.lib.ntu.edu.tw/handle/123456789/600327
標題: | Thermoresponsive SERS Nanocapsules Constructed by Linear-Dendritic Poly(urea/malonamide) for Tunable Biomolecule Detection | 作者: | Cheng Y.-W Chuang W.-H Wang K.-S Tseng W.-C Chiu W.-Y Wu C.-H Liu T.-Y RU-JONG JENG |
關鍵字: | dendritic polymer;lower critical solution temperature;silver nanoparticles;surface-enhanced Raman scattering;thermoresponsive;Hydrophilicity;Metabolism;Metal nanoparticles;Micelles;Nanocapsules;Raman scattering;Silver nanoparticles;Surface scattering;Urea;Analytes;Critical solution temperature;Enhanced Raman scattering;Linear dendritic;Low critical solution temperature;Lower critical;Malonamides;Surface enhanced Raman;Surface-enhanced raman scattering;Thermo-responsive;Dendrimers | 公開日期: | 2022 | 卷: | 4 | 期: | 1 | 起(迄)頁: | 240-249 | 來源出版物: | ACS Applied Polymer Materials | 摘要: | In this work, thermoresponsive core–shell micelle-embedded silver nanoparticles (AgNPs) were prepared from a series of monodisperse linear-dendritic poly(urea/malonamide). Through efficient iterative synthesis, well-defined dendritic amphiphiles bearing dual functionality provide nucleation sites as excellent templates for immobilizing AgNPs on one end, while oligoethers anchor water to stabilize these micelles in water as polymer dispersions. During the heating process, linear-dendritic poly(urea/malonamide) with various ratios of hydrophilic/hydrophobic segments resulted in the size-dependent lowest critical solution temperature (LCST), ranging from 72 to 54 °C in aqueous media. As a result, the gap distances between AgNPs could be manipulated, resulting in a stronger hot spot effect using thermoresponsive nanocapsules for surface-enhanced Raman scattering (SERS) analysis. Consequently, the signal was enhanced at temperatures over the LCST. For AgNPs@TD-G1.5 thermoresponsive SERS nanocapsules, an ?33 times enhancement during the LCST transition was obtained. The high sensitivity and stability of the intelligent AgNPs@thermoresponsive SERS nanocapsules endow them with great potential in the rapid SERS detection of small-molecule analytes by adsorbing analytes at room temperature (below the LCST) and encapsulating the analytes into micelles at high temperatures (above the LCST) in the application of monitoring trace-level and diverse analytes. ? 2021 American Chemical Society |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121681750&doi=10.1021%2facsapm.1c01226&partnerID=40&md5=e4db8838d6b637e41676f5a1f15c6582 https://scholars.lib.ntu.edu.tw/handle/123456789/600327 |
ISSN: | 26376105 | DOI: | 10.1021/acsapm.1c01226 |
顯示於: | 高分子科學與工程學研究所 |
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