https://scholars.lib.ntu.edu.tw/handle/123456789/605996
Title: | Clinical characteristics of naturally Babesia gibsoni infected dogs: A study of 60 dogs | Authors: | Liu P.-C Lin C.-N BI-LING SU |
Keywords: | Babesia gibsoni;Clinical characteristics;M121I;Risk factor;Taiwan;bilirubin;liver enzyme;acute pancreatitis;anaplasmosis;animal experiment;animal model;anorexia;Article;atopic dermatitis;blood transfusion;coinfection;controlled study;enzyme activity;enzyme linked immunosorbent assay;gene mutation;genotype;heart failure;hematocrit;hematoma;hepatomegaly;human granulocytic anaplasmosis;hyperthermia;hypertransaminasemia;leukocyte count;leukocyte differential count;lymphocyte;mean corpuscular hemoglobin;monocytosis;neutrophil count;neutrophilia;nonhuman;platelet count;polymerase chain reaction;retina detachment;retrospective study;risk factor;seizure;sequence analysis;thrombocytopenia;vomiting | Issue Date: | 2022 | Journal Volume: | 28 | Source: | Veterinary Parasitology: Regional Studies and Reports | Abstract: | Babesia gibsoni is increasingly recognized globally as a cause of canine tick-borne anemic disease; however, only a few clinical reports of naturally acquired infection are available. In this systematic study of dogs presenting with B. gibsoni infection, clinical and laboratory data were collected for dogs with PCR-confirmed B. gibsoni infection admitted to the National Taiwan University Veterinary Teaching Hospital (NTUVH) from January 2014 through December 2015. Of the 60 dogs recruited, 20 (33.3%) had concurrent disease and 40 (66.7%) had only B. gibsoni infection. The severity of anemia in B. gibsoni infected dogs with concurrent or without concurrent infection was not significantly different. The most commonly observed hematological abnormalities were anemia (49/60, 81.7%) and thrombocytopenia (37/60, 61.7%). Of 49 dogs, 24 (49%) had severe to very severe anemia (PCV < 20%). The main biochemical abnormalities included hyperglobulinemia (28/53, 52.8%), hyperbilirubinemia (10/28, 35.7%) and elevated hepatic enzyme activity (7/48, 14.6%). In addition, 2 of the 60 the client-owned dogs and 5 of the 33 B. gibsoni-positive stray dogs were detected as having a naturally atovaquone-resistant strain, using the SimpleProbe? assay. The study results provide a useful clinical presentation of B. gibsoni infection and raise the issue of the naturally atovaquone-resistant strain currently existing in Taiwan. ? 2021 The Authors |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121430949&doi=10.1016%2fj.vprsr.2021.100675&partnerID=40&md5=51dcf3f4b19abef516f93d49adf2411d https://scholars.lib.ntu.edu.tw/handle/123456789/605996 |
ISSN: | 24059390 | DOI: | 10.1016/j.vprsr.2021.100675 |
Appears in Collections: | 臨床動物醫學研究所 |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.