https://scholars.lib.ntu.edu.tw/handle/123456789/606013
標題: | Malignant Perivascular Epithelioid Cell Tumour in a Savannah Monitor (Varanus exanthematicus) | 作者: | Hsu C.-W Lee A.-H Lien C.-Y HUI-WEN CHANG |
關鍵字: | animals;immunohistochemistry;perivascular epithelioid cell tumour;savannah monitor;melan A;animal;case report;epithelioid histiocyte;lizard;male;perivascular epithelioid cell tumor;sarcoma;veterinary medicine;Animals;Epithelioid Cells;Lizards;Male;MART-1 Antigen;Perivascular Epithelioid Cell Neoplasms;Sarcoma | 公開日期: | 2021 | 卷: | 188 | 起(迄)頁: | 26-31 | 來源出版物: | Journal of Comparative Pathology | 摘要: | A 9-year-old male captive savannah monitor (Varanus exanthematicus) with a history of general debility was submitted for necropsy. Grossly, there were multiple white masses in the colon, mesorchium and tracheal adventitia. Histologically, the lesions were composed of epithelioid to spindloid neoplastic cells arranged in sheets to interlacing and interwoven bundles, and separated by abundant myxoid material or extensive stromal hyalinization and fibrosis with occasional chondroid metaplasia. Perivascular infiltration of epithelioid neoplastic cells was occasionally seen. Neoplastic cells were immunopositive for alpha-smooth muscle actin, melan-A and S100. The unique histological features and concurrent myogenic and melanocytic immunophenotypes suggest a malignant perivascular epithelioid cell tumour. To our knowledge, this is the first report of perivascular epithelioid cell tumours in a non-human species. ? 2021 Elsevier Ltd |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114842427&doi=10.1016%2fj.jcpa.2021.08.003&partnerID=40&md5=9414f301f3bb9fb08e92f057839b56c5 https://scholars.lib.ntu.edu.tw/handle/123456789/606013 |
ISSN: | 00219975 | DOI: | 10.1016/j.jcpa.2021.08.003 |
顯示於: | 分子暨比較病理生物學研究所 |
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