https://scholars.lib.ntu.edu.tw/handle/123456789/606471
標題: | Multiphoton imaging of autofluorescent advanced glycation end product formation in porcine aorta | 作者: | Lin C.-J.C.-J Kang J.W So P.T.C CHEN-YUAN DONG |
關鍵字: | Artery; Autofluorescence; Glycation; Multiphoton imaging; Blood vessels; Glucose; Glycosylation; Advanced glycation end products; Autofluorescence; D-galactose; Direct contact; Human physiology; Multi-photon microscopy; Multiphoton imaging; Porcine aorta; Sugar industry | 公開日期: | 2021 | 卷: | 11648 | 來源出版物: | Progress in Biomedical Optics and Imaging - Proceedings of SPIE | 摘要: | Exposure of tissues to sugar lead to the formation of advanced glycation end products (AGEs), contributing to diabetic complications. In human physiology, the vasculature is in direct contact with blood, thus the effect of diabetes is expected to be most severe with the vasculature. In this study, we incubated excised porcine aorta in D-glucose, Dgalactose, and D-fructose solutions. Multiphoton microscopy shows that for Days 4 to 48 incubation, autofluorescence is constant along the aorta sections, suggesting that monosaccharide diffusion is rapid when compared to the rate of fluorescent AGE formation. ? 2021 SPIE. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107816980&doi=10.1117%2f12.2583607&partnerID=40&md5=692259c3edb2a8f7fffeae7287dc3429 https://scholars.lib.ntu.edu.tw/handle/123456789/606471 |
ISSN: | 16057422 | DOI: | 10.1117/12.2583607 |
顯示於: | 物理學系 |
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