https://scholars.lib.ntu.edu.tw/handle/123456789/606902
標題: | Polyol-assisted synthesis of spinel-type magnesium cobalt oxide nanochains for voltammetric determination of the antipsychotic drug thioridazine | 作者: | Koventhan C Vinothkumar V Chen S.-M Veerakumar P Lin K.-C. KING-CHUEN LIN |
關鍵字: | Antipsychotic drug;Electrochemical sensor;MgCo2O4;Nanoparticles;Polyol method;Alcohols;Chemical detection;Cost effectiveness;Cyclic voltammetry;Drug delivery;Electrochemical impedance spectroscopy;Electrochemical sensors;Field emission microscopes;Fourier transform infrared spectroscopy;Magnesium compounds;Scanning electron microscopy;X ray photoelectron spectroscopy;Cobalt oxides;Cost effective;Effective synthesis;Electrochemicals;Nanochains;Polyol methods;Spinel-type;Thioridazine;Voltammetric determination;Cobalt compounds | 公開日期: | 2021 | 卷: | 898 | 來源出版物: | Journal of Electroanalytical Chemistry | 摘要: | In this work, a cost-effective, simple and scalable synthesis of nanostructured magnesium cobalt oxide (MgCo2O4) was presented by various methods. The structural morphology was evaluated by powder X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), Raman, Fourier-transform infrared spectrometry (FTIR), and X-ray photoelectron spectroscopy (XPS). Further, electrochemical measurements by electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), and differential pulse voltammetry (DPV) revealed that the MgCo2O4-modified electrode showed good sensitivity (0.895 ?A ?M?1 cm?2), a wide linear range (0.5–1415.8 μM) and a relatively low detection limit (0.047 μM) towards the electrochemical determination of thioridazine (TZ, antipsychotic drug). Loading catalyst, pH, scan rate, and peak potential of TZ were optimized. The proposed sensor features excellent anti-interference ability, good cyclic stability, high reproducibility, and repeatability. The system has also been successfully applied for the detection of TZ in blood serum samples. ? 2021 Elsevier B.V. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114122673&doi=10.1016%2fj.jelechem.2021.115600&partnerID=40&md5=a31ca65502b99032993c10dad5d4e9d1 https://scholars.lib.ntu.edu.tw/handle/123456789/606902 |
ISSN: | 15726657 | DOI: | 10.1016/j.jelechem.2021.115600 |
顯示於: | 化學系 |
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