A high temporal/spatial resolution neuro-architecture study of rodent brain by wideband echo planar imaging
Journal
Scientific Reports
Journal Volume
11
Journal Issue
1
Date Issued
2021
Author(s)
Abstract
Latest simultaneous multi-slice (SMS) methods greatly benefit MR efficiency for recent studies using parallel imaging technique. However, these methods are limited by the requirement of array coils. The proposed Coherent Wideband method, which employs an extended field of view to separate multiple excited slices, can be applied to any existing MRI instrument, even those without array coils. In this study, the Coherent Wideband echo-planar imaging method was implemented on 7?T animal MRI to exhibit comprehensive enhancements in neuro-architecture, including diffusion tensor imaging (DTI) and functional MR studies (fMRI). Under the same scan time, the time-saving effect can be manipulated to increase the number of averages for DTI SNR improvement, reducing fractional anisotropy difference by 56.9% (from 0.072 to 0.041) and the deviation angle by 64% (from 25.3° to 16.2°). In summary, Coherent Wideband Echo Planar Imaging (EPI) will provide faster, higher resolution, thinner slice, or higher SNR imaging for precision neuro-architecture studies. ? 2021, The Author(s).
Subjects
animal experiment
article
brain
diffusion tensor imaging
echo planar imaging
fractional anisotropy
nonhuman
rodent
animal
anisotropy
computer assisted diagnosis
devices
diagnostic imaging
male
nuclear magnetic resonance imaging
procedures
rat
signal noise ratio
Animals
Anisotropy
Brain
Diffusion Tensor Imaging
Echo-Planar Imaging
Image Interpretation, Computer-Assisted
Magnetic Resonance Imaging
Male
Rats
Signal-To-Noise Ratio
SDGs
Type
journal article