https://scholars.lib.ntu.edu.tw/handle/123456789/608170
標題: | Programmed Death Ligand 2 Gene Polymorphisms Are Associated With Lung Adenocarcinoma Risk in Female Never-Smokers | 作者: | SHENG-KAI LIANG Chien, Li-Hsin Chang, Gee-Chen Tsai, Ying-Huang Su, Wu-Chou Chen, Yuh-Min Huang, Ming-Shyan Lin, Hsien-Chih Fang, Wen-Tsen Hung, Hsiao-Han Jiang, Shih-Sheng Chen, Chih-Yi KUAN-YU CHEN Chang, I-Shou Hsiung, Chao A Chen, Chien-Jen PAN-CHYR YANG |
關鍵字: | carcinogenesis; lung adenocarcinoma; programmed death ligand-2; pulmonary tuberculosis; single nucleotide polymorphism | 公開日期: | 2021 | 出版社: | FRONTIERS MEDIA SA | 卷: | 11 | 來源出版物: | Frontiers in oncology | 摘要: | Lung cancer in never-smokers is a distinct disease associated with a different genomic landscape, pathogenesis, risk factors, and immune checkpoint inhibitor responses compared to those observed in smokers. This study aimed to identify novel single nucleotide polymorphisms (SNPs) of programmed death-1 (encoded by PDCD1) and its ligands, programmed death ligand 1 (CD274) and 2 (PDCD1LG2), associated with lung cancer risk in never-smoking women. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/608170 | ISSN: | 2234-943X | DOI: | 10.3389/fonc.2021.753788 |
顯示於: | 醫學系 |
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