Optic nerve sheath diameter changes at high altitude and in acute mountain sickness: meta-regression analyses
Journal
British Journal of Ophthalmology
Date Issued
2020
Author(s)
Abstract
BACKGROUND/AIMS: To assess changes in optic nerve sheath diameter (ONSD) at high altitude and in acute mountain sickness (AMS). METHODS: Cochrane Library, EMBASE, Google Scholar and PubMed were searched for articles published from their inception to 31st of July 2020. Outcome measures were mean changes of ONSD at high altitude and difference in ONSD change between subjects with and without AMS. Meta-regressions were conducted to investigate the relation of ONSD change to altitude and time spent at that altitude. RESULTS: =89.4%). CONCLUSION: Our analysis shows that ONSD changes correlate with altitude and tend to increase in subjects with AMS. Small study number and high heterogeneity are the limitations of our study. Further large prospective studies are required to verify our findings.
Publisher
BMJ Publishing Group
Type
journal article