Performance analysis and operational experience of [F-18]FDG production with cassette-type modules in four hospitals of Taiwan

Abstract

The performance of FASTlab synthesizers and three-year operational experience at four hospitals in Taiwan were analyzed and summarized. [18F]FDG was daily produced with about 80% (EOB) of RCY and USP-compliant specification at four centers in Taiwan. The easiness to operate the cassette and high RCY of produced [18F]FDG are the main advantages for clinical use at the PET center of hospitals, but some underlying defects of the synthesizer or cassettes should be paid attention to and proactively scrutinized, such as cassette leakage and low tC18 trapping yield.