https://scholars.lib.ntu.edu.tw/handle/123456789/611873
標題: | The estimation of cerebral metabolic rate of O2 from Near Infra-Red Spectroscopy | 作者: | Payne S.J. STEPHEN JOHN PAYNE |
關鍵字: | Computer simulation;Information analysis;Parameter estimation;Physiological models;Spectroscopic analysis;Cerebral metabolic rate;Clinical tools;Haemoglobin;Oxygen saturation;Metabolism | 公開日期: | 2005 | 卷: | 7 VOLS | 起(迄)頁: | 3974-3977 | 來源出版物: | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings | 摘要: | The accurate estimation of cerebral metabolic rate of O2 (CMRO2) is still an unavailable but highly desired clinical tool. The addition of a further experimental variable to Near Infra-Red Spectroscopy (NIRS) allows more information to be gained than has previously been possible. A physiological model is presented here that can be used to estimate CMRO2 from measurements of oxy- and deoxy- haemoglobin and oxygen saturation. It is shown that under steady state conditions, CMRO2 can be estimated accurately, despite the system of equations being underdetermined, partly since the parameters that have to be provided are physiologically meaningful and thus unlikely to vary over a wide range. Initial simulations under dynamic conditions seem to support the hypothesis that dynamic changes in CMRO2 can also be estimated accurately, although this is still work in progress. ?2005 IEEE. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-33846907424&doi=10.1109%2fiembs.2005.1615332&partnerID=40&md5=7ba67ff2acf71102ac93288b8e62509d https://scholars.lib.ntu.edu.tw/handle/123456789/611873 |
DOI: | 10.1109/iembs.2005.1615332 |
顯示於: | 應用力學研究所 |
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