https://scholars.lib.ntu.edu.tw/handle/123456789/614778
標題: | Proteasome inhibitors restore the STAT1 pathway and enhance the expression of MHC class I on human colon cancer cells | 作者: | YI-HSIN LIANG KUO-HSING CHEN JIA-HUEI TSAI Cheng, Yung-Ming Lee, Chang-Cheng Kao, Chiu-Hwa Chan, Kuang-Yu Chen, Yeh-Ting Hsu, Wen-Ling KUN-HUEI YEH |
關鍵字: | Colorectal cancer; Interferon-γ (IFN-γ); Major histocompatibility complex (MHC) class I; Proteasome inhibitors; STAT1; Tumor infiltrating lymphocytes (TILs) | 公開日期: | 10-十一月-2021 | 出版社: | BMC | 卷: | 28 | 期: | 1 | 來源出版物: | Journal of biomedical science | 摘要: | A new strategy, particularly a novel combination, for immunotherapy in microsatellite stable metastatic colorectal cancer (mCRC) treatment needs to be formulated. Studies on the interferon-γ (IFN-γ)/ Janus kinase (JAK)/ signal transducer and activator of transcription (STAT)1 pathway provide new directions in this regard. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/614778 | ISSN: | 1021-7770 | DOI: | 10.1186/s12929-021-00769-9 |
顯示於: | 醫學院附設癌醫中心醫院(臺大癌醫) |
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