https://scholars.lib.ntu.edu.tw/handle/123456789/618546
標題: | Safety and antibody response of recipients who unexpectedly received undiluted prime dose of BNT162b2 COVID-19 vaccine in Taiwan | 作者: | WANG-HUEI SHENG Wang, Chung-Cheng Chu, Ching-Chi Lin, Yueh-Juh SUI-YUAN CHANG Ieong, Si-Man SHAN-CHWEN CHANG |
關鍵字: | Adverse events; Coronavirus disease 2019 (COVID-19); Immune response; Undiluted BNT162b2 vaccine | 公開日期: | 2023 | 來源出版物: | Journal of the Formosan Medical Association = Taiwan yi zhi | 摘要: | We reported 25 recipients (14 females and 11 males) aged from 18 to 65 years who unexpectedly received a primary dose of undiluted BNT162b2 vaccine (180 μg). The most common adverse reactions included injection site pain (n = 22), followed by fever (9), fatigue (8), chest tightness (6), and dizziness (6). The most common laboratory abnormalities were anemia (n = 4) and elevated liver transaminase level (4), followed by abnormal leukocyte counts (3) and elevated D-dimer level (3). The adverse reactions and laboratory abnormalities of these recipients were mild and spontaneously recovered within a few weeks. Significant elevations of anti-SARS-CoV-2 spike IgG titers after a booster dose of the BNT162b2 were found. Similar to reports of BNT162b2 clinical trials, the adverse reactions and laboratory abnormalities of these recipients were mild, and they spontaneously recovered within a few weeks. These results provide clinical and immunological effects of undiluted BNT162b2 vaccine inoculation. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/618546 | ISSN: | 0929-6646 | DOI: | 10.1016/j.jfma.2022.07.009 |
顯示於: | 醫學檢驗暨生物技術學系 |
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