Renin-angiotensin system gene polymorphisms predict the risk of stroke in patients with atrial fibrillation: a 10-year prospective follow-up study
Journal
Heart rhythm
Journal Volume
11
Journal Issue
8
Pages
1384-1390
Date Issued
2014-08
Author(s)
Chang, Shu-Hsuan
Tseng, Chuen-Den
Abstract
Little evidence is available regarding the impact of genetic polymorphisms on the risk of stroke in patients with atrial fibrillation (AF). Angiotensin II plays a pathophysiologic role in prothrombotic atrial endocardial remodeling.
Subjects
Atrial fibrillation; Pharmacogenetics; Polymorphisms; Prospective; Renin–angiotensin system; Stroke
Publisher
ELSEVIER SCIENCE INC
Type
journal article