https://scholars.lib.ntu.edu.tw/handle/123456789/621837
Title: | KCNJ5 Somatic Mutation Is Associated With Higher Aortic Wall Thickness and Less Calcification in Patients With Aldosterone-Producing Adenoma | Authors: | BO-CHING LEE Kang, Victor Jing-Wei CHIEN-TING PAN Huang, Jia-Zheng Lin, Yu-Li Chang, Yi-Yao CHENG-HSUAN TSAI Chou, Chia-Hung ZHENG-WEI CHEN CHE-WEI LIAO Chiu, Yu-Wei VIN-CENT WU CHI-SHENG HUNG CHIN-CHEN CHANG YEN-HUNG LIN the TAIPAI Study Group |
Keywords: | KCNJ5 somatic mutation; aortic calcification; humans; hypertension; primary aldosteronism | Issue Date: | 2-Mar-2022 | Publisher: | FRONTIERS MEDIA SA | Journal Volume: | 13 | Start page/Pages: | 830130 | Source: | Frontiers in endocrinology | Abstract: | Primary aldosteronism (PA) is the most common type of secondary hypertension, and it is associated with a higher rate of cardiovascular complications. KCNJ5 somatic mutations have recently been identified in aldosterone-producing adenoma (APA), however their influence on vascular remodeling and injury is still unclear. The aim of this study was to investigate the association between KCNJ5 somatic mutation status and vascular status. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/621837 | ISSN: | 1664-2392 | DOI: | 10.3389/fendo.2022.830130 |
Appears in Collections: | 醫學系 |
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