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  1. NTU Scholars
  2. 醫學院
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Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/623073
Title: Validity of ICD9-CM codes to diagnose chronic obstructive pulmonary disease from National Health Insurance claim data in Taiwan
Authors: Ho, T.-W.
SHENG-YUAN RUAN 
CHUN-TA HUANG
Tsai, Y.-J.
Lai, F.
FEI-PEI LAI 
CHONG-JEN YU
Keywords: Chronic obstructive pulmonary disease; Database; International classification of diseases code; Taiwan; Validity
Issue Date: 2018
Publisher: Dove Medical Press Ltd.
Journal Volume: 13
Start page/Pages: 3055-3063
Source: International Journal of COPD
Abstract: 
Purpose: Claim data from Taiwan’s National Health Insurance (NHI) database have previously been utilized in the study of COPD. However, there are limited data on the positive predictive value of claim data for COPD diagnosis. Therefore, this study aimed to characterize and validate the COPD cohort identified from the NHI research database. Methods: This cross-sectional study compared records from claim data with those from a medical center. From 2007 to 2014, a COPD cohort was constructed from claim data using ICD9-CM codes for COPD. The diagnostic positive predictive value of these data was assessed with reference to physician-verified COPD. In addition, a multivariate logistic regression model was built to identify independent factors associated with the positive predictive value of COPD diagnosis by claim data. Results: During the 8-year study period, a total of 12,127 subjects met the criterion of having two or more outpatient codes in 1 year or one or more inpatient COPD codes in their claim data. Of this total, the diagnosis of COPD was verified by physicians in 7,701 (63.5%) subjects. Applying a more stringent criterion - three or more outpatient codes or two or more inpatient codes - improved the diagnostic positive predictive value to 72.2%. Age ≥65 years and a claim for spirometry were the two most important factors associated with the positive predictive value of claim-data-defined COPD. Adding spirometry testing to diagnostic ICD9-CM codes for COPD increased the positive predictive value to 84.6%. Conclusion: This study emphasizes the importance of validation of disease-specific diagnosis prior to applying an administrative database in clinical studies. It also indicates the limitation of ICD9-CM codes alone in recognizing COPD patients within the NHI research database. © 2018 Ho et al.
URI: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054889370&doi=10.2147%2fCOPD.S174265&partnerID=40&md5=57bd0d5ec8b59da2493e6e28a1bc713c
https://scholars.lib.ntu.edu.tw/handle/123456789/623073
ISSN: 1176-9106
DOI: 10.2147/COPD.S174265
SDG/Keyword: [SDGs]SDG3
age; aged; Article; chronic obstructive lung disease; cohort analysis; comorbidity; controlled study; cross-sectional study; diagnostic accuracy; female; health insurance; human; ICD-9-CM; major clinical study; male; physician; predictive value; retrospective study; sex; spirometry; Taiwan; chronic obstructive lung disease; classification; comparative study; factual database; insurance; International Classification of Diseases; middle aged; multivariate analysis; procedures; public health; risk assessment; sex factor; statistical model; statistics and numerical data; university hospital; validation study; very elderly; Age Factors; Aged; Aged, 80 and over; Cross-Sectional Studies; Databases, Factual; Female; Hospitals, University; Humans; Insurance Claim Review; International Classification of Diseases; Logistic Models; Male; Middle Aged; Multivariate Analysis; National Health Programs; Predictive Value of Tests; Pulmonary Disease, Chronic Obstructive; Retrospective Studies; Risk Assessment; Sex Factors; Spirometry; Taiwan
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臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

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