Serum cytokine/chemokine profiles predict hepatitis B reactivation in HBV/HCV co-infected subjects receiving direct-acting antiviral agents
Journal
Journal of the Formosan Medical Association = Taiwan yi zhi
Journal Volume
121
Journal Issue
5
Pages
920-929
Date Issued
2022-05
Author(s)
Abstract
Direct-acting antiviral agents (DAAs) have revolutionized the paradigm for HCV treatment. However, patients with HBV and HCV co-infection receiving DAAs are at significant risk of HBV reactivation, with limited literature addressing the roles of serum chemokines/chemokines. We aimed to explore the profiles and predictive value of serum cytokines/chemokines regarding HBV reactivation in this clinical setting.
Subjects
Acute flare; Co-infection; C–C motif chemokine ligand 2; Interferon-gamma; TNF-alpha
SDGs
Publisher
ELSEVIER TAIWAN
Type
journal article