Serum PIVKA-II and alpha-fetoprotein at virological remission predicts hepatocellular carcinoma in chronic hepatitis B related cirrhosis
Journal
Journal of the Formosan Medical Association = Taiwan yi zhi
Journal Volume
121
Journal Issue
3
Pages
703-711
Date Issued
2022-03
Author(s)
Peng, Cheng-Yuan
Chang, Shan-Han
Abstract
The risk of hepatocellular carcinoma (HCC) is reduced but not eliminated after nucleos(t)ide analogue (NA) therapy in chronic hepatitis B (CHB). We aimed to investigate the role of serum Prothrombin Induced by Vitamin K Absence or Antagonist-II (PIVKA-II) and alpha-fetoprotein in predicting HCC and mortality in cirrhotic CHB patients at virological remission (VR) following NA therapy.
Subjects
AFP; DCP; Des-carboxyprothrombin; Liver cancer; Prothrombin induced by vitamin K Absence or antagonist-II
Publisher
ELSEVIER TAIWAN
Type
journal article