Dosing Pattern and Early Cumulative Dose of Liposomal Irinotecan in Metastatic Pancreatic Cancer: A Real-World Multicenter Study
Journal
Frontiers in oncology
Journal Volume
12
Date Issued
2022
Author(s)
Su, Yung-Yeh
Chiang, Nai-Jung
Li, Chung-Pin
Yen, Chia-Jui
Chou, Wen-Chi
Chen, Jen-Shi
Chiu, Tai-Jan
Chen, Yen-Yang
Chuang, Shih-Chang
Bai, Li-Yuan
Chiu, Chang-Fang
Peng, Cheng-Ming
Chan, De-Chuan
Chiu, Sz-Chi
Yang, Yi-Hsin
Shan, Yan-Shen
Chen, Li-Tzong
Abstract
This multicenter, real-world cohort study aimed to evaluate the effectiveness of early cumulative dose administration and dosing pattern of liposomal irinotecan plus fluorouracil/leucovorin (nal-IRI+5-FU/LV) in patients with gemcitabine-refractory metastatic pancreatic ductal adenocarcinoma (mPDAC).
Subjects
dose escalation strategy; dose intensity; nal-IRI; pancreatic cancer; real world
Publisher
FRONTIERS MEDIA SA
Type
journal article