High-throughput determination of RNA structures
Journal
Nature Reviews Genetics
Journal Volume
19
Journal Issue
10
Pages
615-634
Date Issued
2018
Author(s)
Abstract
RNA performs and regulates a diverse range of cellular processes, with new functional roles being uncovered at a rapid pace. Interest is growing in how these functions are linked to RNA structures that form in the complex cellular environment. A growing suite of technologies that use advances in RNA structural probes, high-throughput sequencing and new computational approaches to interrogate RNA structure at unprecedented throughput are beginning to provide insights into RNA structures at new spatial, temporal and cellular scales. © 2018, Macmillan Publishers Ltd., part of Springer Nature.
Other Subjects
article; DNA probe; high throughput sequencing; RNA structure; animal; biology; chemistry; conformation; genetics; human; metabolism; procedures; sequence analysis; RNA; Animals; Computational Biology; High-Throughput Nucleotide Sequencing; Humans; Nucleic Acid Conformation; RNA; Sequence Analysis, RNA
Type
review