https://scholars.lib.ntu.edu.tw/handle/123456789/626013
標題: | Antifungal Sesquiterpenoids from Michelia formosana Leaf Essential Oil against Wood-Rotting Fungi | 作者: | Wu C.-C Huang S.-L CHUN-HAN KO HUI-TING CHANG |
關鍵字: | antifungal activity; Michelia formosana; sesquiterpenoids; wood-rotting fungi | 公開日期: | 2022 | 卷: | 27 | 期: | 7 | 來源出版物: | Molecules | 摘要: | Michelia formosana (Kanehira) Masamune is a broad-leaved species widespread in East Asia; the wood extract and its constituents possess antifungal activity against wood-decay fungi. Antifungal activities of leaf essential oil and its constituents from M. formosana were investigated in the present study. Bioassay-guided isolation was applied to isolate the phytochemicals from leaf essential oil. 1D and 2D NMR, FTIR, and MS spectroscopic analyses were applied to elucidate the chemical structures of isolated compounds. Leaf essential oil displayed antifungal activity against wood decay fungi and was further separated into 11 fractions by column chromatography. Four sesquiterpenoids were isolated and identified from the active fractions of leaf essential oil through bioassay-guided isolation. Among these sesquiterpenoids, guaiol, bulnesol, and β-elemol have higher antifungal activity against brown-rot fungus Laetiporus sulphureus and white-rot fungus Lenzites betulina. Leaf essential oil and active compounds showed better antifungal activity against L. sulphureus than against L. betulina. The molecular structure of active sesquiterpenoids all contain the hydroxyisopropyl group. Antifungal sesquiterpenoids from M. formosana leaf essential oil show potential as natural fungicides for decay control of lignocellulosic materials. © 2022 by the authors. Licensee MDPI, Basel, Switzerland. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85127506447&doi=10.3390%2fmolecules27072136&partnerID=40&md5=5e6a0465406263f53e2769ba3af6cf5b https://scholars.lib.ntu.edu.tw/handle/123456789/626013 |
ISSN: | 14203049 | DOI: | 10.3390/molecules27072136 | SDG/關鍵字: | antifungal agent; essential oil; sesquiterpene; chemistry; fungus; Magnolia; microbiology; plant leaf; wood; Antifungal Agents; Fungi; Magnolia; Oils, Volatile; Plant Leaves; Sesquiterpenes; Wood |
顯示於: | 森林環境暨資源學系 |
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