https://scholars.lib.ntu.edu.tw/handle/123456789/626081
Title: | In vivo anti-carcinogenic property of a formulated citrus peel extract | Authors: | Suzawa M Guo L MIN-HSIUNG PAN Ho C.-T Li S. |
Keywords: | Citrus peel extracts; Colon cancer; Gold lotion; Prostate cancer; Skin cancer | Issue Date: | 2014 | Journal Volume: | 4 | Journal Issue: | 3 | Start page/Pages: | 120-129 | Source: | Functional Foods in Health and Disease | Abstract: | Background: Cancer is one of the two leading fatal diseases humans face. Synthesized drugs available for cancer intervention have many limitations in applications and effectiveness and are often associated with serious of side effects, which can further damage the patients' quality of life. Recently, the development of natural-product-based and therapeutically sound anti-cancer agents have gained popularity in the fields of functional and medical foods, which may exhibit advantages of minimal toxicity and multiple active molecular components. Citrus peel or its extract has been reported to have potent pharmacological activities and health benefits because of abundant flavonoids present in citrus fruits, particularly in the peels. Results: The results of these studies demonstrated the efficacy of Gold Lotion (GL), an extract of multiple varieties of citrus peels that contains abundant flavonoids, including a high percentage of polymethoxylflavones (PMFs), which can protect against skin cancer, colon cancer, and prostate cancer in mice. These results are clearly promising and warrant a human trial with GL in future studies. Summary: Briefly, these data have demonstrated that GL is efficacious in preventing and treating cancer in several model systems. This review summarizes the results of currently available data regarding the in vivo anti-cancer activity of GL, and identifies opportunities for subsequent human clinical trials to assess preventive and therapeutic effects in the near future. © 2011 Functional Foods in Health and Disease. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84946491364&doi=10.31989%2fffhd.v4i3.21&partnerID=40&md5=04558a3a18b236d7f11f150b6165e533 https://scholars.lib.ntu.edu.tw/handle/123456789/626081 |
ISSN: | 23787007 | DOI: | 10.31989/ffhd.v4i3.21 |
Appears in Collections: | 食品科技研究所 |
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