https://scholars.lib.ntu.edu.tw/handle/123456789/626180
標題: | The synthesis of antigens and the production of antibodies against patulin derivatives | 作者: | FUU SHEU Lee O YUAN-TAY SHYU |
關鍵字: | Patulin derivatives; Polyclonal antibody | 公開日期: | 1999 | 卷: | 7 | 期: | 1 | 起(迄)頁: | 65-72 | 來源出版物: | Journal of Food and Drug Analysis | 摘要: | Patulin hemisuccinate (P-HS) was synthesized and conjugated to bovine serum albumin (BSA) as the hapten-protein conjugation for immunization. Polyclonal antibodies were obtained from the antiascites of six immunized mice. Titers and specificity were determined using an indirect ELISA. The results indicated that three of the six mice were better immunized and that the antibodies acted strongly against patulin-hemisuccinate-BSA. Slight ELISA responses of the antibodies against patulin alone showed the potential for developing monoclonal antibodies. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0033032329&partnerID=40&md5=563590e519bcf2ce400198e8bce28c93 https://scholars.lib.ntu.edu.tw/handle/123456789/626180 |
ISSN: | 10219498 | SDG/關鍵字: | bovine serum albumin; hapten; hapten antibody; patulin; patulin hemisuccinate; polyclonal antibody; unclassified drug; animal experiment; antibody production; antibody specificity; antibody titer; antigen binding; article; ascites fluid; controlled study; drug conjugation; drug structure; drug synthesis; female; immunogenicity; intramuscular drug administration; intraperitoneal drug administration; mouse; nonhuman; reaction analysis; subcutaneous drug administration |
顯示於: | 園藝暨景觀學系 |
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