https://scholars.lib.ntu.edu.tw/handle/123456789/626597
Title: | Anti-depressive-like and cognitive impairment alleviation effects of Gastrodia elata Blume water extract is related to gut microbiome remodeling in ApoE-/- mice exposed to unpredictable chronic mild stress | Authors: | Huang, Huai-Syuan Lin, Yu-En Panyod, Suraphan Chen, Rou-An Lin, Ying-Cheng Chai, Laura Min Xuan CHENG-CHIH HSU WEI-KAI WU KUAN-HUNG LU Huang, Yun-Ju LEE-YAN SHEEN |
Keywords: | Cognitive impairment; Depression; Gastrodia elata Blume water extract; Gut microbiome; Unpredictable chronic mild stress model | Issue Date: | 10-Feb-2023 | Journal Volume: | 302 | Journal Issue: | Pt B | Source: | Journal of ethnopharmacology | Abstract: | Gastrodia elata Blume (GE) is a traditional Chinese dietary therapy used to treat neurological disorders. Gastrodia elata Blume water extract (WGE) has been shown to ameliorate inflammation and improve social frustration in mice in a chronic social defeat model. However, studies on the anti-depressive-like effects and cognitive impairment alleviation related to the impact of WGE on the gut microbiome of ApoE-/- mice remain elusive. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/626597 | ISSN: | 03788741 | DOI: | 10.1016/j.jep.2022.115872 |
Appears in Collections: | 化學系 |
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