https://scholars.lib.ntu.edu.tw/handle/123456789/626604
標題: | A Randomized Controlled Trial of R-Form Verapamil Added to Ongoing Metformin Therapy in Patients with Type 2 Diabetes | 作者: | CHIH-YUAN WANG KUO-CHIN HUANG CHIA-WEN LU Chu, Chih-Hsun Huang, Chien-Ning Chen, Harn-Shen Lee, I-Te Chen, Jung-Fu Chen, Ching-Chu Chen, Chung-Sen Hsieh, Chang-Hsun Tien, Kai-Jen Chien, Hung-Yu Huang, Yu-Yao Hsu, Jui-Pao Shane, Guang-Tzuu Chang, Ai-Ching Wu, Yen-Chieh Sheu, Wayne Huey-Herng |
關鍵字: | HbA1c; R-form verapamil; antidiabetic drug; metformin; type 2 diabetes | 公開日期: | 28-九月-2022 | 出版社: | ENDOCRINE SOC | 卷: | 107 | 期: | 10 | 起(迄)頁: | E4063 | 來源出版物: | The Journal of clinical endocrinology and metabolism | 摘要: | There is a medical need for effective insulin-independent antidiabetic drugs that can promote pancreatic β-cell function and have a low risk of hypoglycemia in type 2 diabetes mellitus (T2DM) patients. R-form verapamil (R-Vera), which is able to enhance the survival of β-cells and has higher cardiovascular safety margin compared with racemic verapamil, was developed as a novel approach for T2DM treatment. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/626604 | ISSN: | 0021-972X | DOI: | 10.1210/clinem/dgac436 |
顯示於: | 醫學系 |
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