https://scholars.lib.ntu.edu.tw/handle/123456789/626609
標題: | Next-generation pathology practices with mass spectrometry imaging | 作者: | Chung, Hsin-Hsiang Huang, Penghsuan Chen, Chih-Lin Lee, Chuping CHENG-CHIH HSU |
關鍵字: | clinical; disease diagnosis; mass spectrometry imaging; pathology | 公開日期: | 11-七月-2022 | 出版社: | WILEY | 來源出版物: | Mass spectrometry reviews | 摘要: | Mass spectrometry imaging (MSI) is a powerful technique that reveals the spatial distribution of various molecules in biological samples, and it is widely used in pathology-related research. In this review, we summarize common MSI techniques, including matrix-assisted laser desorption/ionization and desorption electrospray ionization MSI, and their applications in pathological research, including disease diagnosis, microbiology, and drug discovery. We also describe the improvements of MSI, focusing on the accumulation of imaging data sets, expansion of chemical coverage, and identification of biological significant molecules, that have prompted the evolution of MSI to meet the requirements of pathology practices. Overall, this review details the applications and improvements of MSI techniques, demonstrating the potential of integrating MSI techniques into next-generation pathology practices. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/626609 | ISSN: | 0277-7037 | DOI: | 10.1002/mas.21795 |
顯示於: | 化學系 |
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