https://scholars.lib.ntu.edu.tw/handle/123456789/626639
標題: | Characteristics and local risk factors of community-acquired and health-care-associated Staphylococcus aureus pneumonia | 作者: | LI-NA LEE Chou, Wen-Ru JANN-YUAN WANG Kuo, Yen-Liang Chang, Chi-Yueh Lee, Yi-Chien Tung, Shao-Hsien Tsao, Wen-Ching Chao, Ke-Yun Liu, Wei-Lun |
關鍵字: | MORTALITY; EPIDEMIOLOGY; SCABIES; ADULTS; HOST | 公開日期: | 4-十一月-2022 | 出版社: | NATURE PORTFOLIO | 卷: | 12 | 期: | 1 | 來源出版物: | Scientific reports | 摘要: | This study aims at identifying characteristics, risk factors and mortality of community-acquired (CAP) and health-care-associated pneumonia (HCAP) by Staphylococcus aureus (S. aureus). We retrieved adults with S. aureus CAP or HCAP diagnosed by blood or pleural effusion culture in 2.6 years, and compared with those of Streptococcus pneumoniae (S. pneumoniae) CAP or HCAP diagnosed by blood or respiratory culture, or urine antigen. We found 18 patients with CAP and 9 HCAP due to S. aureus (female 33%, 66.6 ± 12.4 years-old), and 48 patients with CAP and 15 HCAP due to S pneumoniae (female 41%, 69.5 ± 17.5 years). Diabetes mellitus (52% vs. 24%, p = 0.019), hemodialysis (11% vs. 0%, p = 0.046), skin lesions (44% vs. 0%, p < 0.001), cavitary nodules (37% vs. 1.6%, p < 0.001) and pleural effusions (48% vs. 18%, p = 0.007) were more common in staphylococcal than pneumococcal group. Three patients with staphylococcal pneumonia had acute myocardial infarction. Pneumonia severity index (139 ± 52 vs. 109 ± 43, p = 0.005) and 30-day mortality (41% vs. 9.5%, p = 0.001) were higher in staphylococcal group. Multivariate analysis showed underlying disease (especially cancer and cirrhosis), risk class 4/5, altered mentality, shock and bilateral pneumonia were risk factors for 30-day mortality. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/626639 | ISSN: | 2045-2322 | DOI: | 10.1038/s41598-022-23246-1 |
顯示於: | 醫學系 |
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