Isoniazid level and flu-like symptoms during rifapentine-based tuberculosis preventive therapy: A population pharmacokinetic analysis
Journal
British journal of clinical pharmacology
Date Issued
2023
Author(s)
Abstract
A population pharmacokinetic (PPK) study of the correlation of adverse drug reactions (ADRs) with the 3HP regimen (weekly high-dose rifapentine plus isoniazid for 12 doses) for latent tuberculosis infection (LTBI) remains lacking. The purpose of this study is to determine the association of rifapentine or isoniazid concentration and ADRs.
Subjects
flu-like symptoms; isoniazid; population pharmacokinetics; rifapentine; tuberculosis preventive therapy
SDGs
Publisher
WILEY
Type
journal article