https://scholars.lib.ntu.edu.tw/handle/123456789/627209
標題: | Safety and efficacy of cabozantinib for patients with advanced hepatocellular carcinoma who advanced to Child-Pugh B liver function at study week 8: a retrospective analysis of the CELESTIAL randomised controlled trial | 作者: | El-Khoueiry, Anthony B Meyer, Tim ANN-LII CHENG Rimassa, Lorenza Sen, Suvajit Milwee, Steven Kelley, Robin Kate Abou-Alfa, Ghassan K |
關鍵字: | Cabozantinib; Child–Pugh B; Hepatocellular carcinoma | 公開日期: | 9-四月-2022 | 出版社: | BMC | 卷: | 22 | 期: | 1 | 來源出版物: | BMC cancer | 摘要: | Patients with hepatocellular carcinoma (HCC) and Child-Pugh B liver cirrhosis have poor prognosis and are underrepresented in clinical trials. The CELESTIAL trial, in which cabozantinib improved overall survival (OS) and progression-free survival (PFS) versus placebo in patients with HCC and Child-Pugh A liver cirrhosis at baseline, was evaluated for outcomes in patients who had Child-Pugh B cirrhosis at Week 8. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/627209 | ISSN: | 1471-2407 | DOI: | 10.1186/s12885-022-09453-z |
顯示於: | 腫瘤醫學研究所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。