Cross-protective humoral immunity to coronaviruses from SARS coronavirus 2-naïve sera of children with Kawasaki disease
Journal
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
Date Issued
2022-10-01
Author(s)
Lin, Tzu-Yi
Lee, Yu-Lin
Wu, Kun-Lang
Yang, Ming-Chun
Huang, Chi-Nan
Fu, Chun-Min
Huang, Li-Ming
Liu, Hong-Hsing
Abstract
SARS coronavirus 2 (SARS-CoV-2)-associated multi-system inflammatory syndrome in children indicates that viruses can trigger a Kawasaki disease (KD)-like hyperinflammation. A plausible hypothesis was that coronavirus-specific 'holes' in humoral immunity could cause both diseases.
Subjects
Coronavirus; Humoral immunity; Kawasaki disease: MIS-C; SARS-CoV-2
SDGs
Type
journal article