https://scholars.lib.ntu.edu.tw/handle/123456789/627805
標題: | Ceiling effect of clomiphene citrate on the testosterone to estradiol ratio in eugonadal infertile men | 作者: | Liao, Yian YI-KAI CHANG SHUO-MENG WANG HONG-CHIANG CHANG |
關鍵字: | SECONDARY HYPOGONADISM; THERAPY | 公開日期: | 2022 | 出版社: | PUBLIC LIBRARY SCIENCE | 卷: | 17 | 期: | 1 | 來源出版物: | PloS one | 摘要: | The testosterone to estradiol ratio (T/E2 ratio) reportedly exerts a stronger effect on semen quality and sexual desire than does testosterone alone. Clomiphene citrate is a selective estrogen receptor modulator that has long been used as an empirical treatment option in the management of idiopathic oligozoospermia. Clomiphene may change the hypothalamus-pituitary-gonad axis and result in the alteration of the T/E2 ratio. No reliable data are available regarding the change in the T/E2 ratio after clomiphene use in eugonadism. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/627805 | ISSN: | 1932-6203 | DOI: | 10.1371/journal.pone.0262924 |
顯示於: | 醫學系 |
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