https://scholars.lib.ntu.edu.tw/handle/123456789/627905
標題: | Quantitative Evaluation of Age-Related Effects Based on Oxygenation Dynamic Signals During the Wisconsin Card Sorting Test | 作者: | Huang, Yi-Hua CHUNG-MING CHEN Wang, YM Sun, CW |
關鍵字: | Senior citizens; Hemodynamics; Task analysis; Aging; Detectors; Sorting; Monitoring; Near-infrared spectroscopy; functional brain signal; brain age; Wisconsin card sorting test; CEREBRAL HEMOGLOBIN OXYGENATION; VERBAL-FLUENCY TASK; PREFRONTAL CORTEX; BRAIN ACTIVATION; OLDER-ADULTS; BOLD FMRI; PERFORMANCE; NIRS; DEPENDENCY; HEALTHY | 公開日期: | 2021 | 出版社: | IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC | 卷: | 27 | 期: | 4 | 來源出版物: | IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS | 摘要: | The present study investigated age-related changes in the time-varying hemodynamics of the prefrontal cortex by using near-infrared spectroscopy (NIRS). NIRS is a real-time spectroscopic method used to measure functional hemodynamic responses related to neural activation in the brain. The prefrontal hemodynamic responses of 17 young adults and 21 elderly adults were monitored while they completed the Wisconsin card sorting test (WCST). The results revealed a slower activation pattern in oxyhemoglobin concentrations in the elderly group than in the young group. Furthermore, quantified results revealed timevarying trends in hemodynamic responses. The findings imply that age-related decline in hemodynamic responses may contribute to poorer performance during cognitive tasks. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/627905 | ISSN: | 1077-260X | DOI: | 10.1109/JSTQE.2020.3019283 |
顯示於: | 醫學工程學研究所 |
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