https://scholars.lib.ntu.edu.tw/handle/123456789/627961
標題: | International recommendations for plasma Epstein-Barr virus DNA measurement in nasopharyngeal carcinoma in resource-constrained settings: lessons from the COVID-19 pandemic | 作者: | Lee, Victor Ho-Fun Adham, Marlinda Ben Kridis, Wala Bossi, Paolo Chen, Ming-Yuan Chitapanarux, Imjai Gregoire, Vincent Hao, Sheng Po Ho, Cheryl Ho, Gwo Fuang Kannarunimit, Danita Kwong, Dora Lai-Wan Lam, Ka-On Lam, Wai Kei Jacky Le, Quynh-Thu Lee, Anne Wing-Mui Lee, Nancy Y Leung, To-Wai Licitra, Lisa Lim, Darren Wan-Teck Lin, Jin-Ching Loh, Kwok Seng PEI-JEN LOU Machiels, Jean-Pascal Mai, Hai-Qiang Mesía, Ricard Ng, Wai-Tong Ngan, Roger Kai-Cheong Tay, Joshua K Tsang, Raymond King-Yin Tong, Chi-Chung Wang, Hung-Ming Wee, Joseph T |
公開日期: | 十二月-2022 | 卷: | 23 | 期: | 12 | 來源出版物: | The Lancet. Oncology | 摘要: | The effects of the COVID-19 pandemic continue to constrain health-care staff and resources worldwide, despite the availability of effective vaccines. Aerosol-generating procedures such as endoscopy, a common investigation tool for nasopharyngeal carcinoma, are recognised as a likely cause of SARS-CoV-2 spread in hospitals. Plasma Epstein-Barr virus (EBV) DNA is considered the most accurate biomarker for the routine management of nasopharyngeal carcinoma. A consensus statement on whether plasma EBV DNA can minimise the need for or replace aerosol-generating procedures, imaging methods, and face-to-face consultations in managing nasopharyngeal carcinoma is urgently needed amid the current pandemic and potentially for future highly contagious airborne diseases or natural disasters. We completed a modified Delphi consensus process of three rounds with 33 international experts in otorhinolaryngology or head and neck surgery, radiation oncology, medical oncology, and clinical oncology with vast experience in managing nasopharyngeal carcinoma, representing 51 international professional societies and national clinical trial groups. These consensus recommendations aim to enhance consistency in clinical practice, reduce ambiguity in delivering care, and offer advice for clinicians worldwide who work in endemic and non-endemic regions of nasopharyngeal carcinoma, in the context of COVID-19 and other airborne pandemics, and in future unexpected settings of severe resource constraints and insufficiency of personal protective equipment. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/627961 | ISSN: | 14702045 | DOI: | 10.1016/S1470-2045(22)00505-8 |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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