https://scholars.lib.ntu.edu.tw/handle/123456789/628230
標題: | Age-related changes in ocular vestibular-evoked myogenic potentials via galvanic vestibular stimulation and bone-conducted vibration modes | 作者: | CHIH-MING CHANG YI-HO YOUNG Cheng, Po Wen |
關鍵字: | Aging | NI latency | NI-pI amplitude | NI-pI interval | PI latency | Vestibulo-ocular reflex | 公開日期: | 1-十二月-2012 | 出版社: | TAYLOR & FRANCIS LTD | 卷: | 132 | 期: | 12 | 起(迄)頁: | 1295 | 來源出版物: | Acta Oto-Laryngologica | 摘要: | Conclusion: The age-related changes in ocular vestibular-evoked myogenic potentials (oVEMPs) elicited by galvanic vestibular stimulation (GVS) and bone-conducted vibration (BCV) might be attributed to the morphological degeneration of the vestibular system. Objective: This study employed GVS and BCV modes for eliciting oVEMPs in healthy subjects to explore the effect of aging on the vestibulo-ocular reflex (VOR) pathway. Methods: Sixty-nine healthy subjects (aged 22-69 years) were divided into 5 groups of 12-19 subjects by decades of age. All subjects underwent oVEMPs using GVS and BCV modes. The prevalence and parameters of oVEMPs, including nI latency, pI latency, nI-pI interval, and nI-pI amplitude were measured and compared. Results: The prevalences of GVS-oVEMPs had nonsignificant differences among all age groups, whereas that of BCV-oVEMPs in the over-60 group was significantly lower than those in the under-60 groups. In GVS-oVEMPs, the group over 60 years had significantly longer nI, pI latencies, and smaller amplitudes when compared with those under 60 years. In BCV-oVEMPs, the nI and pI latencies in the over-60 group were significantly longer than those of the under-60 groups, while the nI-pI amplitudes of groups over 50 years were significantly smaller than those of groups under 50 years. All oVEMP parameters exhibited significant differences between GVS- and BCV-oVEMPs in each age group. © 2012 Informa Healthcare. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/628230 | ISSN: | 00016489 | DOI: | 10.3109/00016489.2012.708437 |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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