Daratumumab monotherapy for patients with relapsed or refractory natural killer/T-cell lymphoma, nasal type: an open-label, single-arm, multicenter, phase 2 study
Journal
Journal of hematology & oncology
Journal Volume
14
Journal Issue
1
Pages
25
Date Issued
2021-02-15
Author(s)
Huang, Huiqiang
Zhu, Jun
Kim, Tae Min
Yoon, Dok Hyun
Cho, Seok-Goo
Eom, Hyeon Seok
Lim, Soon Thye
Yeh, Su-Peng
Song, Yuqin
Kwong, Yok Lam
Kim, Jin Seok
Jin, Jie
Shi, Yuankai
Kim, HyeJin
Qing, Min
Zhou, Tianyuan
Gao, Grace
Dong, Zongqi
Qi, Ming
Kim, Won Seog
Abstract
Natural killer/T-cell lymphoma (NKTCL) is a disease with limited treatment options and poor outcomes. Daratumumab monotherapy demonstrated clinical activity in a single-patient case report. We present data from the primary analysis of a phase 2 study of daratumumab monotherapy in relapsed or refractory (R/R) NKTCL.
Subjects
CD38; Daratumumab; NK/T-cell lymphoma
Publisher
BMC
Type
journal article